Five men have been arrested on suspicion of attempted murder after a stabbing victim was left in a life-threatening condition.
St Peter's Street is closed at the junction with Yeovil Road in Lowestoft while police investigate the incident.
Suffolk Police said officers were called at 11.35pm on Saturday, May 1 by the East Anglian Air Service after receiving reports a 21-year-old man had suffered a single stab wound near to the East Coast College.
The victim was taken initially to the James Paget University Hospital and then to Addenbrooke's Hospital in Cambridge.
He remains there with life-threatening injuries.
Following the stabbing, five men - all from Lowestoft and aged between 20 and 24 - have been arrested for attempted murder.
They were taken to police investigation centres in Great Yarmouth, Martlesham and Bury St Edmunds where they remain while enquiries continue.
Forensic officers were seen at St Peter's Street on Sunday lunchtime, while police officers still on scene into the afternoon - closing the road for 500 yards from near the roundabout with Rotterdam Road to the junction with Winnipeg Road and Beresford Road.
Residents at the eastern end of the St Peter's Street were largely unaware of the incident until seeing police at the scene in the morning.
One resident said: "I was lying in bed when I saw all the flashing lights.
"It is a shock to see that right outside your front door.”
Another said: "As I was leaving for work this morning at about 6am the road was still closed off.
"I saw about 10 police cars, forensics and what looked like an armed copper."
Police believe the men are known to each other and there is no wider risk to the public. Officers are not looking for anyone else in connection with the incident.
Anyone with information is being asked to contact Lowestoft CID on 101 quoting reference 37/22320/21, or online via their website.
This is the second stabbing to happen on St Peter's Street in the last 12 months. In October 2020, a man in his late teens was stabbed as trouble flared outside the former Boots pharmacy.
Four teenagers were arrested before later being released under investigation.
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